Hypokalemia in Diabetic Ketoacidosis: Risks & Care

Hypokalemia in Diabetic Ketoacidosis: Risks & Care Diabetic ketoacidosis is a serious complication of diabetes that occurs when the body produces high levels of acidic ketones. Hypokalemia, characterized by low potassium levels, often accompanies DKA and can lead to severe health consequences if not managed promptly.

Understanding the connection between hypokalemia and DKA is crucial. Electrolyte imbalances, such as low potassium levels, are common in DKA due to the body’s inability to properly regulate these essential nutrients. Additionally, metabolic acidosis, resulting from increased ketone production, further disrupts the body’s electrolyte balance.

Insulin deficiency plays a significant role in the development of hypokalemia in DKA. Insufficient insulin production hampers the body’s ability to transport potassium into cells, resulting in low potassium levels. This highlights the importance of addressing insulin deficiency as a crucial step in managing hypokalemia.


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The risks and complications associated with hypokalemia in DKA cannot be understated. Irregular heart rhythms, muscle weakness, and even life-threatening cardiac events can occur when potassium levels are severely depleted. It is vital to detect and manage hypokalemia promptly to prevent further health complications.

Managing hypokalemia in DKA requires adherence to specific guidelines. These guidelines encompass the use of potassium supplements and the administration of intravenous therapy to restore and maintain adequate potassium levels. Proper monitoring and adjustment of potassium levels are essential components of effective management.

Various treatment options are available for hypokalemia in DKA, including oral and intravenous potassium supplementation. The choice of treatment depends on the severity of the condition and the individual’s overall health status. Healthcare professionals at Acibadem Healthcare Group specialize in tailoring treatment plans to the unique needs of each patient.


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Several risk factors contribute to the development of hypokalemia in DKA. Uncontrolled diabetes, prolonged vomiting, and dehydration are common triggers. Recognizing and addressing these risk factors is crucial to prevent hypokalemia and its associated complications.

Hypokalemia in DKA can lead to severe complications affecting multiple body systems. Cardiac arrhythmias, muscle weakness, and respiratory failure are among the potential consequences of untreated or poorly managed hypokalemia. Early intervention and close monitoring are essential to mitigate these risks.

Recognize hypokalemia in DKA as a medical emergency that requires immediate intervention. Seeking prompt medical attention is vital to ensure the timely management of hypokalemia and prevent potentially life-threatening complications.

Effective care strategies for managing hypokalemia in DKA include adopting a multidisciplinary approach and providing patient education. By working collaboratively with healthcare professionals and empowering patients, we can enhance the quality of care and optimize patient outcomes.

In conclusion, understanding and addressing hypokalemia in diabetic ketoacidosis are crucial for optimal patient care. Acibadem Healthcare Group is committed to providing comprehensive healthcare services to individuals affected by hypokalemia in DKA. Stay tuned for further sections of this article where we delve deeper into this topic and provide valuable insights into the risks, complications, management, and care strategies for hypokalemia in DKA.

Understanding Hypokalemia and Diabetic Ketoacidosis

In order to fully comprehend the relationship between hypokalemia and diabetic ketoacidosis (DKA), it is crucial to delve into the intricacies of these conditions and their underlying mechanisms. Hypokalemia refers to a deficiency of potassium in the bloodstream, while diabetic ketoacidosis is a serious complication of diabetes characterized by high blood sugar levels and the presence of ketones.

Electrolyte imbalances, including hypokalemia, frequently occur in individuals with DKA. Electrolytes such as potassium play a vital role in numerous bodily functions, including nerve and muscle cell communication, maintaining fluid balance, and regulating heart rhythm. Therefore, any disruption in electrolyte levels can have profound effects on the body’s overall functioning.

In the context of DKA, hypokalemia is commonly observed due to several factors. First and foremost, the lack of insulin production or inadequate insulin levels leads to a shift in the body’s metabolism. This metabolic alteration, known as metabolic acidosis, contributes to the development of DKA. Notably, the production of ketones as a result of fat breakdown in the absence of insulin exacerbates the acidosis and further depletes potassium levels.

Additionally, electrolyte imbalances, including hypokalemia, may also arise from the excessive loss of fluids and electrolytes through osmotic diuresis. This occurs when high blood sugar levels cause an increase in urine production. As a consequence, potassium is excreted more rapidly, resulting in lower levels in the bloodstream.

To fully grasp the impact and significance of hypokalemia in DKA, it is essential to understand the repercussions of electrolyte imbalances and metabolic acidosis on the body. The next section will explore insulin deficiency and its influence on potassium levels, shedding light on the intricate relationship between these factors.

Electrolyte Levels in Diabetic Ketoacidosis

Electrolyte Normal Range DKA
Potassium (K+) 3.6-5.2 mEq/L Low levels due to insulin deficiency and increased urinary excretion
Sodium (Na+) 135-145 mEq/L Normal or decreased levels due to fluid loss
Chloride (Cl-) 98-106 mEq/L Normal or decreased levels due to fluid loss
Bicarbonate (HCO3-) 22-26 mEq/L Low levels due to metabolic acidosis
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Insulin Deficiency and Potassium Levels

Insulin plays a crucial role in maintaining normal potassium levels in the body. Insufficient insulin production, commonly referred to as insulin deficiency, can lead to imbalances in potassium levels.

When there is an insulin deficiency, the body’s cells are unable to effectively take up glucose from the bloodstream. As a result, the body turns to alternative energy sources like fat breakdown. This process leads to the production of ketones, causing a condition called diabetic ketoacidosis (DKA).

Insulin deficiency in DKA disrupts the normal regulation of potassium within cells. As glucose is unable to enter the cells, this intracellular potassium is pushed into the bloodstream, resulting in hyperkalemia, or high potassium levels in the blood. However, as DKA progresses and the body becomes more acidotic, the kidneys eliminate excess potassium, ultimately leading to hypokalemia, or low potassium levels.

When there is an imbalance in potassium levels, it can have detrimental effects on various bodily functions. Potassium is vital for maintaining proper cellular function, especially in muscle contraction, nerve conduction, and heart rhythm regulation.

To further understand the relationship between insulin deficiency and potassium levels, let’s take a look at an illustrative table:

Insulin Levels Potassium Levels Effects
Normal Normal Proper cellular function
Insulin Deficiency Hyperkalemia Disruption of cellular function
DKA Progression Hypokalemia Potential complications in muscle, nerve, and heart function

This table highlights the correlation between insulin deficiency and potassium levels, showing how insulin deficiency can lead to both hyperkalemia and hypokalemia, impacting various bodily functions.

Recognizing the importance of addressing insulin deficiency and managing potassium imbalances is crucial in the treatment of diabetic ketoacidosis and the prevention of further complications.

Risks and Complications of Hypokalemia in DKA

In diabetic ketoacidosis (DKA), hypokalemia, which refers to low potassium levels in the blood, can pose significant risks and complications. It is important to promptly address and manage hypokalemia to prevent further health issues.

Risks: Hypokalemia in DKA can lead to various risks, including:

  • Cardiac arrhythmias
  • Muscle weakness
  • Increased insulin resistance
  • Impaired kidney function
  • Metabolic acidosis exacerbation

Complications: Complications associated with hypokalemia in DKA can be serious and require immediate attention. Common complications include:

  • Electrolyte imbalances
  • Renal impairment
  • Respiratory distress
  • Neuromuscular abnormalities
  • Cardiovascular abnormalities

The severity of the risks and complications of hypokalemia in DKA highlights the importance of proactive management and treatment. Prompt intervention can help prevent further health deterioration and improve the overall outcome for individuals with DKA.

Effective Management of Hypokalemia in DKA

To effectively manage hypokalemia in DKA, a comprehensive approach is crucial. This includes:

  1. Regular monitoring of potassium levels
  2. Administration of potassium supplements, under medical supervision
  3. Proper hydration and fluid management
  4. Close coordination between healthcare professionals

By closely monitoring potassium levels and ensuring appropriate treatment, healthcare providers can work towards restoring normal potassium balance in individuals with DKA.

Table: Comparing the risks and complications of hypokalemia in DKA

Risks Complications
Cardiac arrhythmias Electrolyte imbalances
Muscle weakness Renal impairment
Increased insulin resistance Respiratory distress
Impaired kidney function Neuromuscular abnormalities
Metabolic acidosis exacerbation Cardiovascular abnormalities

Proper management of hypokalemia can help mitigate these risks and complications, ensuring improved outcomes for individuals with DKA.

Management Guidelines for Hypokalemia in DKA

In order to effectively manage hypokalemia in diabetic ketoacidosis (DKA), it is crucial to follow proper management guidelines. The goal is to restore and maintain balanced potassium levels in the body, ensuring optimal health and preventing further complications. Here are some key guidelines to consider:

1. Identifying and monitoring potassium levels:

Regular monitoring of potassium levels is essential for early detection and management of hypokalemia in DKA. Healthcare professionals should closely monitor the patient’s blood potassium levels and adjust treatment plans accordingly.

2. Treating underlying causes:

Addressing the underlying causes of hypokalemia is crucial for effective management. In the case of DKA, treating the insulin deficiency and metabolic acidosis is essential in restoring potassium balance. Insulin therapy and correction of acidosis play significant roles in managing hypokalemia.

3. Potassium supplementation:

Supplementing potassium orally or intravenously is often necessary to restore potassium levels to a normal range. The dosage and route of administration should be determined by healthcare professionals based on the severity of hypokalemia and the patient’s overall condition.

4. Fluid and electrolyte management:

Proper fluid and electrolyte management is essential in managing hypokalemia in DKA. The administration of intravenous fluids, including electrolytes, plays a crucial role in achieving and maintaining potassium balance. Healthcare professionals should carefully monitor fluid intake, electrolyte levels, and adjust treatment as needed.

5. Monitoring cardiac function:

Hypokalemia can have adverse effects on cardiac function, leading to life-threatening complications. Continuous monitoring of cardiac function, including ECG monitoring, can help identify any abnormalities and guide further treatment strategies.

6. Multidisciplinary approach:

Collaboration between healthcare professionals is vital in the management of hypokalemia in DKA. Endocrinologists, nephrologists, and other specialists should work together to develop a comprehensive treatment plan that addresses not only the potassium imbalance but also the underlying causes and potential complications.

7. Patient education and self-care:

Empowering patients with knowledge about the management of hypokalemia in DKA is crucial for long-term success. Patients should be educated about proper nutrition, medication adherence, and the importance of regular follow-up appointments to monitor potassium levels.

By following these management guidelines, healthcare professionals can effectively address hypokalemia in diabetic ketoacidosis, improving patient outcomes and minimizing the risk of complications.

Treatment Options for Hypokalemia in DKA

When it comes to managing hypokalemia in diabetic ketoacidosis (DKA), there are several treatment options available. The aim of these treatments is to restore and maintain the potassium levels in the body to prevent further complications and promote overall health.

Potassium Supplements

One of the main treatment options for hypokalemia in DKA is the use of potassium supplements. These supplements are available in various forms, including tablets, liquids, and powders. They provide a concentrated source of potassium that can be easily consumed to replenish the body’s potassium levels.

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Intravenous Therapy

In more severe cases of hypokalemia, intravenous (IV) therapy may be necessary. IV therapy involves the administration of potassium directly into the bloodstream, ensuring rapid absorption and immediate effects. This method is often used when oral potassium supplements are not sufficient or cannot be tolerably consumed by the patient.

Other Interventions

Aside from potassium supplements and IV therapy, there may be other interventions used to treat hypokalemia in DKA. These can include adjustments to the patient’s diabetes medications, such as changing the dosage or type of insulin being used. Additionally, addressing any underlying factors contributing to the potassium imbalance, such as managing vomiting or dehydration, may be necessary.

It is important to note that the choice of treatment option will depend on the severity of the hypokalemia and the overall condition of the patient. Healthcare professionals will assess the individual’s needs and develop a personalized treatment plan accordingly.

Treatment Option Description
Potassium Supplements Oral supplements, available in various forms, to restore potassium levels.
Intravenous Therapy Direct administration of potassium into the bloodstream for immediate effects.
Other Interventions Modifications to diabetes medications and addressing underlying factors contributing to hypokalemia.

By implementing these treatment options, healthcare providers can effectively manage hypokalemia in DKA and support patients in their journey towards recovery.

Risk Factors for Hypokalemia in DKA

When it comes to diabetic ketoacidosis (DKA), understanding the risk factors for hypokalemia is crucial. Hypokalemia refers to low levels of potassium in the body and can pose significant health risks for individuals with DKA. By recognizing these risk factors, healthcare professionals can proactively address and manage hypokalemia to prevent further complications.

Uncontrolled Diabetes

Uncontrolled diabetes is a major risk factor for developing hypokalemia in DKA. When blood glucose levels are consistently high, the body’s ability to regulate potassium levels becomes impaired. This imbalance in potassium can lead to hypokalemia and exacerbate the already critical condition of DKA.

Dehydration

Dehydration is another common risk factor for hypokalemia in individuals with DKA. When the body lacks proper hydration, electrolyte imbalances can occur, including a decrease in potassium levels. This further aggravates the condition and necessitates timely intervention to restore the body’s electrolyte balance.

Prolonged Vomiting

Prolonged vomiting is a risk factor that can contribute to hypokalemia in DKA. When individuals with DKA experience persistent vomiting, they can rapidly lose fluids and electrolytes, including potassium. It is essential to address vomiting promptly and provide adequate hydration and potassium supplementation to mitigate the risk of hypokalemia.

By recognizing and addressing these risk factors, healthcare professionals can take proactive steps to prevent and manage hypokalemia in individuals with diabetic ketoacidosis. Timely intervention and comprehensive care are vital in improving patient outcomes and reducing the risk of further complications.

Complications Arising from Hypokalemia in DKA

Hypokalemia, a condition characterized by low potassium levels in the blood, can lead to various complications when it occurs in conjunction with diabetic ketoacidosis (DKA). These complications can have severe implications on the overall health and well-being of individuals with DKA. Let’s explore some of the potential complications arising from hypokalemia in DKA:

1. Impaired Heart Function

Potassium plays a crucial role in maintaining normal heart function. Hypokalemia can disrupt the electrical signals that control the heart’s rhythm, leading to irregular heartbeats, known as arrhythmias. Severe hypokalemia can even increase the risk of cardiac arrest, further highlighting the importance of managing potassium levels in individuals with DKA.

2. Muscle Weakness and Fatigue

Potassium is essential for proper muscle function. When potassium levels are low, muscle weakness and fatigue can occur. This can significantly impact an individual’s mobility and overall quality of life. It is vital to address hypokalemia promptly to prevent the progression of muscle weakness and associated complications.

3. Electrolyte Imbalances

Hypokalemia is often accompanied by other electrolyte imbalances, such as hyponatremia (low sodium levels) or hypocalcemia (low calcium levels). These imbalances can further disrupt normal bodily functions and may lead to complications such as muscle cramps, neurological symptoms, and bone disorders.

4. Increased Risk of Cardiac Arrhythmias

As mentioned earlier, hypokalemia can result in abnormal heart rhythms. These arrhythmias, if left unmanaged, can have serious consequences, including heart failure and sudden cardiac arrest. Individuals with DKA and hypokalemia require close monitoring and appropriate interventions to minimize the risk of cardiac complications.Hypokalemia in Diabetic Ketoacidosis: Risks & Care

5. Impaired Respiratory Function

Potassium is also essential for proper muscle function in the respiratory system. Hypokalemia can affect the muscles involved in breathing, leading to respiratory weakness and difficulty in maintaining adequate oxygen levels. Managing potassium levels is crucial to prevent respiratory complications in individuals with DKA.

6. Worsening Metabolic Acidosis

Hypokalemia can exacerbate metabolic acidosis, a condition characterized by an imbalance of acids and bases in the body. Untreated or poorly managed metabolic acidosis can have detrimental effects on various organs and bodily functions, making it crucial to address hypokalemia promptly.Hypokalemia in Diabetic Ketoacidosis: Risks & Care

These complications highlight the importance of recognizing and managing hypokalemia in individuals with DKA. Prompt intervention, close monitoring, and appropriate treatment strategies can help mitigate these complications and improve overall outcomes for individuals with DKA.

Complication Impact
Impaired Heart Function Increased risk of arrhythmias and cardiac arrest
Muscle Weakness and Fatigue Reduced mobility and quality of life
Electrolyte Imbalances Disruption of bodily functions, muscle cramps, and neurologic symptoms
Increased Risk of Cardiac Arrhythmias Potential for heart failure and sudden cardiac arrest
Impaired Respiratory Function Respiratory weakness and difficulty in maintaining oxygen levels
Worsening Metabolic Acidosis Imbalance of acids and bases in the body affecting organ function

Recognizing Hypokalemia as a Medical Emergency

Hypokalemia in diabetic ketoacidosis is a serious medical condition that requires immediate attention. The depletion of potassium levels can lead to life-threatening complications, making it essential to recognize hypokalemia as a medical emergency.

When hypokalemia occurs in the context of diabetic ketoacidosis, it exacerbates the already precarious balance of electrolyte and acid-base disturbances in the body. This electrolyte imbalance, along with metabolic acidosis, can have detrimental effects on various organ systems.

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Healthcare professionals play a critical role in recognizing and responding to hypokalemia promptly. Early identification of symptoms, such as muscle weakness, fatigue, and abnormal heart rhythms, is crucial for timely intervention and appropriate management.Hypokalemia in Diabetic Ketoacidosis: Risks & Care

Immediate treatment is necessary to restore potassium levels and stabilize the patient’s condition. Healthcare providers will closely monitor electrolyte status, administer intravenous potassium supplements, and address any underlying factors contributing to hypokalemia.

Furthermore, it is imperative to address the underlying cause of hypokalemia in diabetic ketoacidosis, such as insulin deficiency. Insulin therapy plays a crucial role in restoring potassium balance by facilitating the movement of potassium from the extracellular space back into the cells.

Recognizing hypokalemia as a medical emergency requires a multidisciplinary approach involving doctors, nurses, and other healthcare professionals. Timely and effective collaboration ensures proper management and reduces the risk of severe complications.

Signs of Hypokalemia in Diabetic Ketoacidosis Potential Complications
  • Muscle weakness
  • Fatigue
  • Cardiac arrhythmias
  • Vomiting
  • Cardiac dysfunction
  • Rhabdomyolysis
  • Renal impairment
  • Neuromuscular abnormalities

In conclusion, hypokalemia in diabetic ketoacidosis should be recognized as a medical emergency due to its potential for severe complications. Healthcare professionals must be vigilant in identifying and responding to hypokalemia promptly to ensure appropriate and timely intervention.

Effective Care Strategies for Hypokalemia in DKA

In managing hypokalemia in diabetic ketoacidosis (DKA), it is crucial to implement effective care strategies that address the underlying electrolyte imbalance while providing comprehensive patient care. A multidisciplinary approach involving healthcare professionals from various specialties can significantly improve patient outcomes and ensure optimal management of hypokalemia in DKA.

One essential care strategy is regular monitoring of potassium levels to accurately assess the severity of hypokalemia and guide appropriate treatment interventions. This can be achieved through frequent blood tests and close collaboration between healthcare providers and laboratory personnel.

Another crucial aspect of care is the administration of potassium supplements to replenish depleted levels. Potassium chloride supplements are commonly used and can be administered orally or intravenously, depending on the severity of the hypokalemia. Close monitoring of potassium levels during supplementation is essential to avoid both excessive potassium levels (hyperkalemia) and persistent depletion.

Additionally, preventing further loss of potassium is essential for effective care. Addressing the underlying cause of the imbalanced potassium levels, such as correcting insulin deficiency in DKA, is paramount. Regular administration of insulin therapy can help restore glucose homeostasis and prevent ongoing potassium loss.

Hypokalemia in Diabetic Ketoacidosis: Risks & Care:Avoidance of Rapid Potassium Repletion

While it is essential to restore potassium levels, it is equally crucial to manage potassium repletion carefully. Rapid repletion of potassium can lead to complications such as cardiac arrhythmias, necessitating cautious administration and monitoring. The use of continuous electrocardiogram (ECG) monitoring during potassium repletion is advisable to promptly identify any abnormalities.

Patient Education and Support

Educating patients about the importance of potassium balance and the role of medication adherence is vital for effective self-care. Patients should understand the risks of non-compliance with prescribed treatments and the potential consequences of uncontrolled hypokalemia in DKA. Providing educational resources, such as brochures or online materials, can empower patients to actively participate in their care and make informed decisions.Hypokalemia in Diabetic Ketoacidosis: Risks & Care

Moreover, providing emotional support to patients and their families is essential in the management of hypokalemia in DKA. Understanding the impact of their condition and addressing any concerns or anxieties can promote patient well-being and overall treatment compliance.

Care Strategies for Hypokalemia in DKA Description
Regular monitoring of potassium levels Close follow-up and tracking of potassium levels through frequent blood tests
Administration of potassium supplements Oral or intravenous administration of potassium chloride to replenish depleted levels
Addressing the underlying cause Correction of insulin deficiency in DKA to restore glucose homeostasis and prevent ongoing potassium loss
Avoidance of rapid potassium repletion Caution in administering potassium to prevent complications such as cardiac arrhythmias
Patient education and support Empowering patients with knowledge and emotional support to actively participate in their care

Hypokalemia in Diabetic Ketoacidosis: Risks & Care:Conclusion

In conclusion, understanding and addressing hypokalemia in diabetic ketoacidosis (DKA) is crucial for ensuring optimal patient care and outcomes. Hypokalemia, an electrolyte imbalance, can have serious implications for individuals with DKA. It is important for healthcare providers to be aware of the risks and complications associated with this condition.

Throughout this article, we have explored the relationship between hypokalemia and DKA, as well as the potential consequences of untreated hypokalemia. We have discussed the importance of timely intervention and outlined management guidelines for addressing potassium imbalances in patients with DKA.

Acibadem Healthcare Group, a renowned healthcare institution, recognizes the significance of comprehensive care for individuals with hypokalemia in DKA. By providing state-of-the-art treatment options and a multidisciplinary approach, Acibadem Healthcare Group aims to ensure the highest level of care and support for patients with this condition.Hypokalemia in Diabetic Ketoacidosis: Risks & Care

By staying informed about hypokalemia in DKA and collaborating with healthcare professionals, we can work towards better management and improved outcomes for individuals affected by this condition. Together, we can make a difference in the lives of patients with hypokalemia in diabetic ketoacidosis.

Hypokalemia in Diabetic Ketoacidosis: Risks & Care:FAQ

What is hypokalemia in diabetic ketoacidosis (DKA)?

Hypokalemia refers to low levels of potassium in the blood. In the context of diabetic ketoacidosis (DKA), which is a serious complication of diabetes, hypokalemia can occur due to electrolyte imbalances and metabolic acidosis.

How does insulin deficiency affect potassium levels?

Insulin deficiency, which is a hallmark of diabetic ketoacidosis (DKA), disrupts the body's ability to regulate potassium levels. Inadequate insulin production leads to decreased cellular uptake of potassium, resulting in hypokalemia.

What are the risks and complications of hypokalemia in DKA?

Hypokalemia in DKA can pose significant risks and complications. It can lead to cardiac arrhythmias, muscle weakness, paralysis, and even life-threatening conditions such as respiratory failure and renal impairment if not promptly addressed.


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