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Scleritis vs Episcleritis: Key Differences

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Scleritis vs Episcleritis: Key Differences
FAQ
What is scleritis? Scleritis is a serious condition characterized by inflammation of the sclera, which is the tough and fibrous outer layer of the eye. It often presents with symptoms such as severe eye pain, redness, blurry vision, and sensitivity to light. Scleritis can be classified into different types, including anterior scleritis, posterior scleritis, and necrotizing scleritis. Accurate differential diagnosis and proper treatment are crucial to prevent complications and manage the condition effectively. What are the causes of eye inflammation and redness? Eye inflammation and redness can be caused by various factors, including infections (such as conjunctivitis or keratitis), allergies, irritants (such as smoke or pollutants), dry eyes, autoimmune disorders, trauma or injury to the eye, and underlying systemic conditions (such as rheumatoid arthritis or lupus). It is important to identify the underlying cause of eye inflammation to determine the most appropriate treatment approach. What are the key differences between scleritis and episcleritis? Scleritis and episcleritis are both forms of eye inflammation, but they differ in their severity and underlying causes. Scleritis is a more serious condition characterized by inflammation of the sclera, the white part of the eye, whereas episcleritis is a milder form of inflammation that affects the episcleral tissues. Scleritis often presents with intense eye pain, redness, and blurred vision, while episcleritis typically causes localized eye redness and mild discomfort. Additionally, scleritis is associated with various underlying conditions such as autoimmune disorders, infections, and connective tissue diseases, whereas episcleritis is often idiopathic and tends to resolve on its own without extensive treatment.

Scleritis vs Episcleritis: Key Differences. Welcome to our comprehensive guide comparing scleritis and episcleritis, two common eye inflammations. If you’ve been experiencing eye redness or discomfort, it’s important to understand the differences between these conditions to seek proper treatment. In this article, we will explore the symptoms, causes, and treatment options for scleritis and episcleritis, helping you make informed decisions about your eye health.

Eye inflammation can be a distressing experience, and understanding the specifics of scleritis and episcleritis can provide valuable insights into managing these conditions effectively. We will delve into the causes and risk factors associated with each condition, highlighting the importance of accurate diagnosis for appropriate treatment approaches.

Furthermore, we will explore the symptoms typically associated with scleritis and episcleritis, helping you recognize these conditions and seek medical attention promptly. It is crucial to distinguish between the two to determine the severity and potential complications that may require different treatment strategies.

In terms of treatment options, we will discuss various approaches for managing scleritis and episcleritis, including both medical interventions and self-care measures. By familiarizing yourself with these options, you can play an active role in the management of your eye inflammation.

If you are concerned about your eye health or suspect you may have scleritis or episcleritis, it is essential to seek proper medical care. Our article will emphasize the significance of personalized care plans and highlight reputable healthcare providers, like the Acibadem Healthcare Group, who specialize in successfully treating eye inflammations.

Read on to discover more about scleritis, episcleritis, and the key differences between the two conditions. Armed with this knowledge, you can take proactive steps towards better eye health and appropriate treatment.

Understanding Eye Inflammation

Before delving into the differences between scleritis and episcleritis, it is important to understand the concept of eye inflammation and its various causes. Ocular inflammation, also known as uveitis, refers to the inflammation of the eye’s uvea, which consists of the iris, ciliary body, and choroid.

Eye redness, a common symptom of ocular inflammation, can be caused by a variety of factors. Some of the most common causes of eye redness include:

  • Allergies: Allergens such as pollen, dust, pet dander, or certain medications can trigger an allergic reaction, leading to eye redness.
  • Infections: Bacterial, viral, or fungal infections can cause inflammation in the eye, resulting in redness and discomfort.
  • Eye conditionsEye conditions such as dry eye syndrome, blepharitis, or corneal ulcers can contribute to eye redness and inflammation.
  • Environmental factors: Environmental factors like smoke, pollution, or exposure to chemicals can irritate the eyes, causing redness and irritation.

The severity and duration of eye redness may vary depending on the underlying cause. In some cases, eye redness may be accompanied by additional symptoms such as itching, burning, tearing, or blurred vision. If you experience persistent or bothersome eye redness, it is recommended to consult an eye care professional for a comprehensive evaluation.

Common Eye Conditions Associated with Redness:

Eye Condition Symptoms Treatment
Conjunctivitis (Pink Eye) Eye redness, itching, discharge Antibiotic eye drops, antihistamines, cold compresses
Subconjunctival Hemorrhage Bright red patch on the white of the eye No treatment required, resolves on its own
Corneal Abrasion Eye redness, pain, foreign body sensation Topical antibiotics, lubricating eye drops, protective eye patch
Uveitis Eye redness, pain, light sensitivity Steroid eye drops, oral medications, immunosuppressive drugs

It’s essential to address eye redness promptly, as untreated inflammation can lead to complications and potentially affect vision. Understanding the causes of eye redness and seeking appropriate medical care can help in managing ocular inflammation effectively.

What is Scleritis?

Scleritis is a serious condition characterized by inflammation of the sclera, which is the white part of the eye. It is a rare but potentially sight-threatening condition that requires prompt medical attention. Scleritis can occur in individuals of all ages, but it is more commonly seen in adults, particularly those with underlying autoimmune disorders. Scleritis vs Episcleritis

One of the key challenges in diagnosing scleritis is distinguishing it from episcleritis, which is a milder form of eye inflammation. While both conditions share some similarities, they differ in terms of severity, symptoms, and potential complications. Accurate differential diagnosis is crucial to ensure proper management and treatment.

The symptoms of scleritis can vary depending on the specific subtype of the condition. However, common symptoms may include:

  • Severe eye pain, which can be constant and worsens with eye movement
  • Eye redness, often described as deep and intense
  • Blurred vision or decreased visual acuity
  • Sensitivity to light (photophobia)
  • Foreign body sensation in the eye

Scleritis can be associated with various underlying conditions, such as autoimmune disorders (e.g., rheumatoid arthritis, systemic lupus erythematosus), infections (e.g., herpes zoster, syphilis), and connective tissue diseases (e.g., scleroderma). In some cases, the exact cause may remain unknown. Scleritis vs Episcleritis

The importance of accurate differential diagnosis cannot be overstated when it comes to scleritis. It is essential to distinguish scleritis from episcleritis, as the treatment strategies and potential complications differ significantly. To achieve an accurate diagnosis, a comprehensive evaluation of the patient’s medical history, symptoms, and clinical examination is essential. Additional tests, such as blood work, imaging studies, and occasionally a biopsy, may be necessary to rule out other underlying causes.

Early detection and appropriate management of scleritis are crucial to prevent complications and preserve vision. Treatment options for scleritis may include:

  1. Topical and systemic corticosteroids: These are commonly used to reduce inflammation and provide symptomatic relief.
  2. Immunosuppressive medications: In cases of severe or recurrent scleritis, immunosuppressive medications may be prescribed to suppress the immune system’s response and control inflammation.
  3. Biologic therapies: Biologic drugs, such as tumor necrosis factor (TNF) inhibitors, may be used in refractory cases of scleritis.
  4. Surgical interventions: In rare cases where medical management is ineffective or complications arise, surgical interventions such as scleral patch grafting or tectonic keratoplasty may be considered. Scleritis vs Episcleritis

Regular monitoring and follow-up with an ophthalmologist specializing in ocular inflammation are essential to ensure the best possible outcome for individuals with scleritis. With the appropriate management and ongoing care, it is possible to control inflammation, alleviate symptoms, and preserve vision.

Scleritis Episcleritis
Severe eye pain Mild discomfort or irritation
Deep and intense eye redness Localized eye redness
Blurred vision and decreased visual acuity No significant impact on vision
Sensitivity to light (photophobia) May experience mild light sensitivity
Foreign body sensation in the eye Occasional sensation of grittiness

Causes and Risk Factors of Scleritis

Scleritis is a condition characterized by inflammation of the sclera, the tough outer layer of the eye. Understanding the causes and risk factors associated with scleritis can help in effectively managing and treating the condition. Scleritis vs Episcleritis

There are several possible causes of scleritis, including:

  • Autoimmune disorders: Rheumatoid arthritis, systemic lupus erythematosus, and Wegener’s granulomatosis are autoimmune diseases that can lead to scleral inflammation.
  • Infections: Herpes zoster, herpes simplex virus, and bacterial infections can contribute to the development of scleritis.
  • Connective tissue diseases: Rheumatoid arthritis, scleroderma, and polyarteritis nodosa are connective tissue diseases that have been linked to scleritis. Scleritis vs Episcleritis
  • Underlying conditions: Conditions such as gout, syphilis, and tuberculosis can also increase the risk of scleritis. Scleritis vs Episcleritis

While the exact cause of scleritis is often not identified, certain risk factors are associated with an increased likelihood of developing the condition. These risk factors include:

  • Age: Scleritis is more common in individuals between the ages of 30 and 60.
  • Gender: Women are more prone to developing scleritis than men.
  • Smoking: Smoking has been identified as a risk factor for scleritis.
  • Underlying health conditions: Individuals with autoimmune disorders or connective tissue diseases are at a higher risk of developing scleritis. Scleritis vs Episcleritis

Early diagnosis and appropriate treatment are crucial for managing scleritis effectively. If you experience symptoms such as eye pain, redness, or blurred vision, it is important to seek medical attention promptly. A healthcare professional will be able to properly diagnose your condition and recommend the most suitable treatment plan.

Causes and Risk Factors of Scleritis

Cause Examples
Autoimmune disorders Rheumatoid arthritis, systemic lupus erythematosus, Wegener’s granulomatosis
Infections Herpes zoster, herpes simplex virus, bacterial infections
Connective tissue diseases Rheumatoid arthritis, scleroderma, polyarteritis nodosa
Underlying conditions Gout, syphilis, tuberculosis

Symptoms of Scleritis

Recognizing the symptoms of scleritis is crucial in obtaining an accurate diagnosis and timely treatment. Scleritis is characterized by inflammation of the sclera, the white part of the eye. Common symptoms of scleritis include:

  • Eye pain: One of the hallmark symptoms of scleritis is severe and throbbing eye pain. The intensity of the pain can vary, ranging from moderate discomfort to excruciating agony.
  • Redness in the eye: Scleritis often leads to noticeable redness on the surface of the eye. The redness is typically localized and can extend beyond the affected area.
  • Blurred vision: Some individuals with scleritis experience blurred vision, making it challenging to focus or see clearly.
  • Sensitivity to light: Scleritis can cause sensitivity to light, known as photophobia, making bright lights and sunlight particularly bothersome.

It’s important to note that the severity and combination of symptoms may vary depending on the type of scleritis. Anterior scleritis, the most common form, is typically associated with more severe symptoms, while posterior and diffuse scleritis may present with milder symptoms. If you experience any of these symptoms, it is crucial to seek medical attention promptly for an accurate diagnosis and appropriate treatment.

Treating Scleritis

Scleritis, a condition characterized by inflammation of the sclera, can be a serious and painful eye condition. Managing scleral inflammation requires personalized treatment plans based on the severity and underlying cause of the condition. The goal of treatment is to reduce inflammation, alleviate symptoms, and prevent complications. There are several treatment options available for scleritis, including: Scleritis vs Episcleritis

1. Corticosteroids

Corticosteroids, such as prednisone or dexamethasone, are commonly prescribed to reduce inflammation in scleritis. These medications can be administered topically as eye drops or orally. The dosage and duration of corticosteroid use will depend on the severity of inflammation and response to treatment.

2. Immunosuppressive Medications

In cases of severe or recurrent scleritis, immunosuppressive medications may be prescribed. These medications help suppress the immune system and reduce inflammation. Methotrexate, cyclosporine, and azathioprine are examples of immunosuppressive drugs that may be used to manage scleral inflammation. Scleritis vs Episcleritis

3. Biologic Therapy

Biologic therapies, such as tumor necrosis factor (TNF) inhibitors, are newer treatment options for scleritis. These medications target specific molecules involved in the inflammatory process, helping to control the immune response. TNF inhibitors like adalimumab and infliximab may be used in cases of refractory scleritis.

4. Surgical Interventions

In some severe cases of scleritis, surgical interventions may be necessary. These include procedures such as scleral patch grafts, amniotic membrane transplantation, or tectonic keratoplasty. Surgical interventions are typically reserved for cases of necrotizing scleritis or scleral thinning where there is a risk of perforation.

It is important to note that the choice of treatment depends on various factors, including the type of scleritis, its severity, and the patient’s overall health. The treating ophthalmologist will evaluate these factors to develop an individualized treatment plan.

Table: Comparison of Treatment Options for Scleritis

Treatment Option Administration Mode of Action Examples
Corticosteroids Topical or oral Reduce inflammation Prednisone, dexamethasone
Immunosuppressive Medications Oral Suppress the immune system Methotrexate, cyclosporine, azathioprine
Biologic Therapy Injected or infused Target specific molecules involved in inflammation Adalimumab, infliximab
Surgical Interventions Surgical procedures Address severe scleritis or scleral thinning Scleral patch grafts, amniotic membrane transplantation, tectonic keratoplasty

It is crucial for individuals with scleritis to work closely with their ophthalmologist to determine the most suitable treatment approach based on their specific condition and overall health. Prompt and appropriate treatment can help manage scleral inflammation, alleviate symptoms, and prevent complications.

Understanding Episcleritis

Episcleritis is a relatively common condition characterized by inflammation of the episcleral tissues, which are the thin layers located between the sclera and the conjunctiva. Unlike scleritis, which affects the deeper layers of the eye, episcleritis is considered a milder and less severe form of eye inflammation.

Episcleritis can occur in individuals of all ages, but it is more commonly observed in young to middle-aged adults. It can affect both eyes or just one eye, and it often presents with localized redness on the surface of the eye. While the exact cause remains unknown in most cases, episcleritis is believed to be related to autoimmune disorders, allergies, and environmental factors.

Symptoms of Episcleritis

The most common symptom of episcleritis is localized redness on the surface of the eye. This redness is typically not associated with pain and tends to be less severe compared to scleritis. Other symptoms may include mild discomfort, sensitivity to light, and a feeling of grittiness in the eye. It is important to note that episcleritis is usually self-limiting and tends to resolve on its own within a few weeks without causing any long-term complications.

Causes of Episcleritis

The exact causes of episcleritis are not always known. However, research suggests that autoimmune disorders, such as rheumatoid arthritis and systemic lupus erythematosus, may play a role in its development. In addition, allergic reactions, infections, and exposure to environmental irritants like smoke or chemicals can trigger episcleritis in some individuals.

Treatment Options for Episcleritis

In most cases, episcleritis does not require extensive medical treatment and tends to resolve on its own. However, there are self-care measures that individuals can take to alleviate symptoms and promote healing. These measures include using over-the-counter artificial tears, applying cold compresses to the affected eye, and avoiding potential irritants. If the symptoms persist or worsen, medical intervention may be necessary, and a healthcare professional can prescribe topical corticosteroids or other medications to manage the inflammation.

Comparing Scleritis and Episcleritis

Scleritis Episcleritis
Affects the deeper layers of the eye (sclera) Affects the thin episcleral tissues
Severe eye pain Mild discomfort
Persistent redness and inflammation Localized redness
May cause vision changes Rarely affects vision
Requires prompt medical treatment Often self-limiting and resolves on its own

Causes and Risk Factors of Episcleritis

Episcleritis, a form of eye inflammation, can be caused by a variety of factors and is often associated with underlying conditions. Understanding these causes and risk factors is essential for accurate diagnosis and effective treatment.

Possible Causes of Episcleritis

Episcleritis can be triggered by various factors, including:

  • Infections: Bacterial, viral, or fungal infections can lead to episcleritis.
  • Autoimmune Diseases: Conditions such as rheumatoid arthritis, lupus, and Sjögren’s syndrome may contribute to the development of episcleritis.
  • Environmental Factors: Exposure to irritants like smoke, pollen, or certain chemicals can cause episcleral inflammation.

Underlying Conditions Associated with Episcleritis

Episcleritis is often seen in patients with underlying conditions, including:

  • Rheumatoid Arthritis: This autoimmune disease can lead to inflammation not only in the joints but also in various parts of the body, including the eyes.
  • Lupus: Systemic lupus erythematosus (SLE) can cause inflammation in multiple organs, including the eyes.
  • Inflammatory Bowel Disease: Conditions like Crohn’s disease and ulcerative colitis may be associated with episcleritis.
  • Sarcoidosis: This inflammatory disease can affect multiple organs and tissues, including the eyes.

These underlying conditions can increase the risk of episcleritis and should be considered during the diagnostic process.

Causes Risk Factors
Infections Bacterial, viral, fungal infections
Autoimmune Diseases Rheumatoid arthritis, lupus, Sjögren’s syndrome
Environmental Factors Exposure to irritants like smoke, pollen, certain chemicals
Underlying Conditions Rheumatoid arthritis, lupus, inflammatory bowel disease, sarcoidosis

Identifying the underlying conditions associated with episcleritis is crucial for developing a comprehensive treatment plan and managing the inflammation effectively. Proper diagnosis and close collaboration between ophthalmologists and other healthcare professionals are essential for successful treatment outcomes.

Symptoms of Episcleritis

Episcleritis is a relatively mild condition characterized by inflammation of the episcleral tissues, which are located between the conjunctiva and the sclera. While the symptoms of episcleritis can vary from person to person, there are some common signs to be aware of.

Localized Eye Redness

One of the key symptoms of episcleritis is localized eye redness. This redness may appear as a pink or purplish hue and is typically limited to a specific area of the eye. Unlike in more severe eye conditions, such as scleritis, the redness does not usually spread to the entire eye.

Mild Discomfort

Episcleritis is commonly associated with mild discomfort or a sensation of irritation in the affected eye. This discomfort is often described as a scratchy or gritty feeling. While it may cause some degree of annoyance, episcleritis is generally not associated with severe pain.

It is important to note that episcleritis generally resolves on its own within a few weeks without the need for extensive treatment. However, if symptoms persist or worsen, it is recommended to seek medical attention for proper diagnosis and management.

Symptoms of Episcleritis
Localized Eye Redness
Mild Discomfort
Eye Pain
Blurred Vision
Sensitivity to Light

Treatment Options for Episcleritis

Episcleritis, a mild form of eye inflammation, can often be managed effectively with various treatment options. In many cases, self-care measures can help alleviate symptoms and promote healing. However, it’s important to understand when medical intervention may be necessary for more severe or persistent cases of episcleritis.

Self-Care Measures

Self-care measures play a crucial role in the management of episcleritis. These simple actions can help reduce discomfort and promote faster healing:

  • Over-the-counter eye drops: Lubricating eye drops can provide relief from dryness and irritation. Look for products specifically designed for dry eye relief or consult with your eye care professional for recommendations.
  • Cold compresses: Applying a cold compress to the affected eye can help reduce inflammation and soothe discomfort. Use a clean, soft cloth or a cold eye mask to gently apply the compress for 10-15 minutes at a time.
  • Avoiding eye irritants: Protecting your eyes from potential irritants such as smoke, dust, and harsh chemicals can help prevent exacerbation of symptoms. Consider wearing protective eyewear or taking breaks in environments with poor air quality.

Medical Intervention

In some cases, self-care measures may not be sufficient to manage episcleritis. If symptoms persist or worsen, it’s important to seek medical intervention. An eye care professional can provide a more comprehensive treatment plan tailored to your specific needs. Medical interventions for episcleritis may include:

  • Prescription eye drops: In more severe cases, your eye care professional may prescribe medicated eye drops to reduce inflammation and alleviate symptoms.
  • Oral medications: In certain situations, oral medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids may be prescribed to help manage episcleritis.
  • Follow-up appointments: Regular follow-up appointments with your eye care professional will ensure proper monitoring of your condition and adjustment of treatment as needed.

Remember, each case of episcleritis is unique, and treatment plans may vary depending on the severity and underlying cause of the inflammation. It’s important to consult with an eye care professional for an accurate diagnosis and personalized treatment recommendations.

Differential Diagnosis of Scleritis and Episcleritis

Accurately differentiating between scleritis and episcleritis is essential for appropriate diagnosis and targeted treatment. Although both conditions involve inflammation of the eye, there are distinct characteristics and diagnostic methods that can help identify each condition.

Understanding Scleritis

Scleritis is a serious eye condition that involves inflammation of the sclera, the white part of the eye. It is often associated with underlying autoimmune disorders, infections, or connective tissue diseases. Scleritis can cause severe eye pain, redness, and blurred vision, and can potentially lead to complications such as corneal ulceration and vision loss.

Exploring Episcleritis

Episcleritis, on the other hand, is a milder form of eye inflammation that affects the episcleral tissues, which lie between the conjunctiva and the sclera. It is typically characterized by localized eye redness, mild discomfort, and a feeling of grittiness. Episcleritis is often self-limiting and tends to resolve without extensive treatment.

Diagnosing the Difference

To distinguish between scleritis and episcleritis, several diagnostic methods may be utilized:

  1. Clinical assessment: A comprehensive evaluation of the patient’s medical history and symptoms can help identify key indicators of each condition. Factors such as the intensity of pain, severity of redness, and associated systemic symptoms can provide valuable insights.
  2. Imaging tests: Imaging techniques such as ultrasound or optical coherence tomography (OCT) may be employed to visualize the affected tissues and identify specific characteristics that differentiate between scleritis and episcleritis.
  3. Biopsy: In certain cases, a biopsy of the affected tissue may be necessary to confirm the diagnosis and rule out other potential causes of eye inflammation.

By utilizing a combination of these diagnostic approaches, eye care specialists can accurately distinguish between scleritis and episcleritis, enabling them to develop tailored treatment plans and ensure the best possible outcomes for patients.

Distinguishing Scleritis and Episcleritis: A Comparative Overview

Scleritis Episcleritis
Severity: Can be severe Severity: Usually mild
Pain: Severe eye pain Pain: Mild discomfort
Redness: Diffuse and often involves the entire eye Redness: Localized to a specific area of the eye
Systemic Symptoms: Often present Systemic Symptoms: Rarely present
Complications: Corneal ulceration, vision loss Complications: None or minimal
Treatment: Immunosuppressive medications, surgery in severe cases Treatment: Over-the-counter eye drops, self-care measures

Through careful examination and consideration of key factors, healthcare providers can accurately distinguish between scleritis and episcleritis, leading to appropriate management and improved patient outcomes.Scleritis vs Episcleritis

Seeking Proper Medical Care

When dealing with eye inflammation, such as scleritis or episcleritis, it is crucial to seek proper medical care for accurate diagnosis and effective treatment. These conditions require expert guidance to manage the symptoms and prevent potential complications.

One notable healthcare provider in this field is Acibadem Healthcare Group, which specializes in eye inflammation treatment and ocular inflammation managementAcibadem Healthcare Group offers a multidisciplinary approach, combining the expertise of ophthalmologists, rheumatologists, and other specialists to provide comprehensive care.

At Acibadem, individualized care plans are tailored to each patient’s specific needs. This ensures that the treatment approach takes into account the severity of the condition, the underlying cause, and the patient’s overall health. With a focus on personalized care, Acibadem Healthcare Group strives to deliver the best possible outcomes for individuals dealing with eye inflammation. Scleritis vs Episcleritis

If you are experiencing symptoms of eye inflammation, such as eye pain, redness, or blurred vision, it is important to reach out to a healthcare professional or consider a consultation with Acibadem Healthcare Group. Remember, seeking proper medical care is essential in managing scleritis and episcleritis effectively and preserving your eye health. Scleritis vs Episcleritis

FAQ

What is scleritis?

Scleritis is a serious condition characterized by inflammation of the sclera, which is the tough and fibrous outer layer of the eye. It often presents with symptoms such as severe eye pain, redness, blurry vision, and sensitivity to light. Scleritis can be classified into different types, including anterior scleritis, posterior scleritis, and necrotizing scleritis. Accurate differential diagnosis and proper treatment are crucial to prevent complications and manage the condition effectively.

What are the causes of eye inflammation and redness?

Eye inflammation and redness can be caused by various factors, including infections (such as conjunctivitis or keratitis), allergies, irritants (such as smoke or pollutants), dry eyes, autoimmune disorders, trauma or injury to the eye, and underlying systemic conditions (such as rheumatoid arthritis or lupus). It is important to identify the underlying cause of eye inflammation to determine the most appropriate treatment approach.

What are the key differences between scleritis and episcleritis?

Scleritis and episcleritis are both forms of eye inflammation, but they differ in their severity and underlying causes. Scleritis is a more serious condition characterized by inflammation of the sclera, the white part of the eye, whereas episcleritis is a milder form of inflammation that affects the episcleral tissues. Scleritis often presents with intense eye pain, redness, and blurred vision, while episcleritis typically causes localized eye redness and mild discomfort. Additionally, scleritis is associated with various underlying conditions such as autoimmune disorders, infections, and connective tissue diseases, whereas episcleritis is often idiopathic and tends to resolve on its own without extensive treatment.

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